This issue features the PDRF Network’s efforts and activities from January to March 2021. A year after the declaration of COVID-19 as a pandemic, new variants of the virus have been detected in over 100 countries, including the Philippines, and found to be more contagious than the original variant, according to research. As the Philippines began its vaccination program, the government continues to impose community quarantine and urge the public to observe minimum health and safety measures to further control the increase of COVID-19 cases. The Philippine Disaster Resilience Foundation (PDRF) and the private sector are working closely with the government, institutions, civil society organizations, and humanitarian groups to further strengthen the implementation of the vaccination program and to increase public uptake through various communication campaigns.